Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.35 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19284306 | 0.88 | TSHR (0.46) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL3643218 | 0.88 | TSHR (0.46) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL983633 | 0.88 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL983333 | 0.88 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL981726 | 0.88 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL984167 | 0.88 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL983265 | 0.88 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL982098 | 0.88 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL984155 | 0.88 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 | |
| SCHEMBL983520 | 0.88 | TSHR (0.50) | TSHRCYSLTR2CYSLTR1GABRA1GABRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147663-A | Oxidative coupling of alkylphenols, alkoxyphenols and naphthols catalyzed by metal complexes of amino carboxylic and amino sulfonic acids | ICI AMERICAS INC. (US) | 1979-04-03 | — | — | US | disclosed |
| US-4130504-A | COPPER COMPOUND, ANIONIC SURFACTANT, ALKALINE MATERIAL AS CATALYST | ICI AMERICAS INC. (US) | 1978-12-19 | — | — | US | disclosed |
| US-4070383-A | COPPER COMPOUND-ANIONIC SURFACTANT-ALKALI METAL COMPOUND CATALYST SYSTEM | ICI AMERICAS INC. (US) | 1978-01-24 | — | — | US | disclosed |
| US-4067890-A | Oxidative coupling of alkylphenols, alkoxyphenols and naphthols catalyzed by metal complexes of amino carboxylic and amino sulfonic acids | ICI AMERICA INC. (US) | 1978-01-10 | — | — | US | disclosed |
| US-4065434-A | Method of preparing high molecular weight polyphenoxy ethers from alkyl phenols | ICI AMERICAS INC. (US) | 1977-12-27 | — | — | US | disclosed |