Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11665731 | 0.96 | TSHR (0.49) | TSHRHPGDHCAR2ATMALDH1A1 | |
| SCHEMBL17997323 | 0.92 | TSHR (0.49) | TSHRHPGDHCAR2ATMALDH1A1 | |
| SCHEMBL2778233 | 0.92 | TSHR (0.58) | TSHRHPGDHCAR2ATMALDH1A1 | |
| SCHEMBL5859055 | 0.92 | TSHR (0.58) | TSHRHPGDHCAR2ATMALDH1A1 | |
| Styrene SCHEMBL11501866 | 0.91 | TSHR (0.40) | TSHRHPGDHCAR2ATMALDH1A1 | |
| SCHEMBL11660144 | 0.89 | TSHR (0.56) | TSHRHCAR2ATMALDH1A1MAPT | |
| Acrylic Acid Ethyl Ester SCHEMBL3421934 | 0.89 | TSHR (0.54) | TSHRHPGDHCAR2ATMALDH1A1 | |
| SCHEMBL5049197 | 0.88 | TSHR (0.59) | TSHRHPGDHCAR2ATMALDH1A1 | |
| SCHEMBL459919 | 0.88 | HCAR2 (0.51) | TSHRHPGDHCAR2ATMALDH1A1 | |
| SCHEMBL9443412 | 0.88 | TSHR (0.63) | TSHRHPGDHCAR2ATMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4164488-A | Aqueous thermosetting acrylic enamel | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-08-14 | — | — | US | disclosed |
| US-4076766-A | AUTOMOBILE BUMPER, ACRYLIC ESTER, POLYESTER, AMINO RESIN CROSSLINKING AGENT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-02-28 | — | — | US | disclosed |
| US-3979535-A | THERMOSETTING ACRYLIC ENAMEL | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-09-07 | — | — | US | disclosed |