Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.35 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | FBP1 | P09467 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | STS | P08842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70624 | 0.78 | GAA (0.67) | GAAGLAKDM4ECYP1A2MAPK1 | |
| SCHEMBL1742098 | 0.75 | GAA (0.46) | GAAGLAKDM4ECYP1A2MAPK1 | |
| SCHEMBL4674954 | 0.73 | GAA (0.56) | GAAGLAKDM4ECYP1A2MAPK1 | |
| SCHEMBL8108947 | 0.72 | GAA (0.55) | GAAGLAKDM4ECYP1A2MAPK1 | |
| SCHEMBL13804463 | 0.71 | GAA (0.58) | GAAGLAKDM4ECYP1A2MAPK1 | |
| SCHEMBL1422945 | 0.71 | KDM4E (0.58) | GAAGLAKDM4ECYP1A2MAPK1 | |
| SCHEMBL3551459 | 0.71 | GAA (0.58) | GAAGLAKDM4ECYP1A2MAPK1 | |
| SCHEMBL9918755 | 0.69 | GAA (0.56) | GAAGLAKDM4ECYP1A2MAPK1 | |
| SCHEMBL1197055 | 0.69 | GAA (0.56) | GAAGLAKDM4ECYP1A2MAPK1 | |
| SCHEMBL17241127 | 0.69 | GAA (0.56) | GAAGLAKDM4ECYP1A2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136253-A | ANTIBIOTICS | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |