Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HTR1D | P28221 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13997648 | 1.00 | HTR1B (0.44) | HTR1BEPHX1HRH1SLC6A4HTR1D | |
| SCHEMBL11307647 | 1.00 | HTR1B (0.44) | HTR1BEPHX1HRH1SLC6A4HTR1D | |
| SCHEMBL7221701 | 1.00 | HTR1B (0.44) | HTR1BEPHX1HRH1SLC6A4HTR1D | |
| SCHEMBL8352992 | 0.97 | HTR1B (0.46) | HTR1BEPHX1HRH1SLC6A4HTR1D | |
| SCHEMBL13997649 | 0.94 | HTR1B (0.44) | HTR1BEPHX1HRH1SLC6A4HTR1D | |
| SCHEMBL12445961 | 0.91 | HTR1B (0.43) | HTR1BEPHX1HRH1SLC6A4HTR1D | |
| SCHEMBL837016 | 0.91 | EPHX1 (0.46) | HTR1BEPHX1HRH1SLC6A4HTR1D | |
| SCHEMBL23267022 | 0.89 | EPHX1 (0.46) | HTR1BEPHX1HRH1SLC6A4HTR1D | |
| SCHEMBL24921945 | 0.89 | HTR1B (0.39) | HTR1BEPHX1HRH1SLC6A4HTR1D | |
| SCHEMBL22144501 | 0.89 | HTR1B (0.39) | HTR1BEPHX1HRH1SLC6A4HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139605-A | A, W-BIS(5-(DIHYDROXYALKYL)AMINOCARBONYL-3-HYDROXYACYLAMINO-2,4,6 -TRIIODOBENZOYLAMINO)-OXAALKANE | BRACCO INDUSTRIA CHIMICA S.P.A. (IT) | 1979-02-13 | — | — | US | disclosed |