Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11514022 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL11514017 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL11513142 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL2384838 | 1.00 | — | — | |
| SCHEMBL11515968 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL11513038 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL11513040 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL11713017 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL11515969 | 1.00 | HDAC4 (0.38) | HDAC4HDAC2HDAC8HDAC6KDM1A | |
| SCHEMBL2384839 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4138583-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS, HYPOTENSIVE AGENTS | MILES LABORATORIES, INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4138582-A | ANTICOAGULANTS, CARDIOVASCULAR DISORDERS, HYPOTENSIVE AGENTS | MILES LABORATORIES, INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4066834-A | Cycloalkenyl analogues of prostaglandins E | MILES LABORATORIES, INC. (US) | 1978-01-03 | — | — | US | disclosed |