Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11517525 | 0.99 | AOC3 (0.38) | AOC3 | |
| Bromide SCHEMBL11517894 | 0.86 | AOC3 (0.40) | AOC3 | |
| Hydrochloric Acid SCHEMBL11514974 | 0.81 | AOC3 (0.39) | AOC3 | |
| SCHEMBL11518518 | 0.78 | AOC3 (0.45) | AOC3 | |
| SCHEMBL11515470 | 0.78 | SMN1; SMN2 (0.39) | AOC3 | |
| SCHEMBL12082694 | 0.73 | AOC3 (0.36) | AOC3 | |
| SCHEMBL7534337 | 0.71 | AOC3 (0.56) | AOC3 | |
| SCHEMBL11517251 | 0.71 | MAPT (0.38) | AOC3 | |
| SCHEMBL7534329 | 0.70 | AOC3 (0.48) | AOC3 | |
| SCHEMBL11518591 | 0.69 | AKT1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4141899-A | ANTIULCER, ANTISECRETORY | SOCIETA' FARMACEUTICI ITALIA S.P.A. (IT) | 1979-02-27 | — | — | US | disclosed |