Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 20/20 | 0.85 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1151012 | 1.00 | P2RY12 (0.85) | P2RY12 | |
| SCHEMBL1151011 | 1.00 | P2RY12 (0.85) | P2RY12 | |
| SCHEMBL1151023 | 1.00 | P2RY12 (0.85) | P2RY12 | |
| SCHEMBL1151702 | 1.00 | P2RY12 (0.85) | P2RY12 | |
| SCHEMBL1151016 | 1.00 | P2RY12 (0.85) | P2RY12 | |
| SCHEMBL1151792 | 0.94 | P2RY12 (0.76) | P2RY12 | |
| SCHEMBL1151786 | 0.94 | P2RY12 (0.76) | P2RY12 | |
| SCHEMBL1151386 | 0.94 | P2RY12 (0.75) | P2RY12 | |
| SCHEMBL1151384 | 0.94 | P2RY12 (0.75) | P2RY12 | |
| SCHEMBL1151164 | 0.92 | P2RY12 (1.00) | P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8466156-B2 | 2-phenyl-4-cyclopropyl-pyrimidine derivatives | ACTELION PHARMACEUTICALS LTD. (CH) | 2013-06-18 | — | — | US | disclosed |
| US-20110028484-A1 | 2-PHENYL-4-CYCLOPROPYL-PYRIMIDINE DERIVATIVES | VIATRIS ASIA PACIFIC PTE. LTD. (SG) | 2011-02-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110028484-A1 | 2-PHENYL-4-CYCLOPROPYL-PYRIMIDINE DERIVATIVES | P2RY12, P2RY13, P2RY4 | P2RY12 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.