Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.62 |
| ▸ | FAP | Q12884 | 3/20 | 0.62 |
| ▸ | ACE | P12821 | 10/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26616424 | 0.86 | PREP (0.67) | PREPFAPACEACE2DPP8 | |
| SCHEMBL26616429 | 0.86 | PREP (0.67) | PREPFAPACEACE2DPP8 | |
| SCHEMBL29749309 | 0.86 | ACE (0.71) | PREPFAPACEACE2 | |
| SCHEMBL3472327 | 0.86 | ACE (0.71) | PREPFAPACEACE2 | |
| SCHEMBL11435575 | 0.86 | ACE (0.71) | PREPFAPACEACE2 | |
| SCHEMBL11515816 | 0.82 | PREP (0.66) | PREPACEACE2 | |
| SCHEMBL10654808 | 0.82 | ACE (0.66) | PREPFAPACEACE2 | |
| SCHEMBL13950902 | 0.81 | PREP (0.56) | PREPFAPACEACE2 | |
| SCHEMBL13928274 | 0.81 | PREP (0.56) | PREPFAPACEACE2 | |
| SCHEMBL8610923 | 0.80 | PREP (0.57) | PREPFAPACEACE2DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176116-A | ELASTASE ENZYME INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1979-11-27 | — | — | US | claimed |
| US-4176116-A | ELASTASE ENZYME INHIBITORS | HOFFMANN-LA ROCHE INC. (US) | 1979-11-27 | — | — | US | disclosed |