Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13531982 | 0.79 | GSK3B (0.61) | GSK3BMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL20221553 | 0.78 | MAPT (0.44) | GSK3BMAPTALDH1A1KDM4EMAPK1 | |
| SCHEMBL2554642 | 0.77 | GSK3B (0.62) | GSK3BMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL10747787 | 0.77 | MAPT (0.62) | GSK3BMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL28964071 | 0.77 | MAPT (0.62) | GSK3BMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11518309 | 0.77 | GSK3B (0.57) | GSK3BMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL11510574 | 0.76 | GSK3B (0.71) | GSK3BALDH1A1MEN1KMT2ACES1 | |
| SCHEMBL240086 | 0.76 | GSK3B (0.71) | GSK3BALDH1A1CES1CA1CA2 | |
| SCHEMBL11074838 | 0.75 | GSK3B (0.53) | GSK3BMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL17702639 | 0.75 | NPC1 (0.53) | GSK3BMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145344-A | BICYCLOMYCIN DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1979-03-20 | — | — | US | disclosed |