Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.66 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.66 |
| ▸ | HPGD | P15428 | 2/20 | 0.66 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.66 |
| ▸ | SLC22A8 | Q8TCC7 | 2/20 | 0.66 |
| ▸ | SLC22A11 | Q9NSA0 | 2/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.66 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.66 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11611919 | 1.00 | MAPT (0.66) | MAPTTDP1NR1I2HPGDSLC22A6 | |
| SCHEMBL11849755 | 1.00 | MAPT (0.66) | MAPTTDP1NR1I2HPGDSLC22A6 | |
| SCHEMBL11794482 | 0.92 | MAPT (0.68) | MAPTTDP1NR1I2HPGDSLC22A6 | |
| SCHEMBL11613589 | 0.91 | MAPT (0.65) | MAPTTDP1NR1I2HPGDSLC22A6 | |
| SCHEMBL11517322 | 0.91 | MAPT (0.61) | MAPTTDP1NR1I2HPGDSLC22A6 | |
| SCHEMBL11616226 | 0.89 | MAPT (0.63) | MAPTTDP1NR1I2HPGDSLC22A6 | |
| SCHEMBL11602491 | 0.89 | MAPT (0.62) | MAPTTDP1NR1I2HPGDSLC22A6 | |
| SCHEMBL11678297 | 0.89 | MAPT (0.62) | MAPTTDP1NR1I2HPGDSLC22A6 | |
| SCHEMBL11503047 | 0.89 | PTGS1 (0.78) | MAPTTDP1NR1I2HPGDSLC22A6 | |
| SCHEMBL11178495 | 0.89 | PTGS1 (0.78) | MAPTTDP1NR1I2HPGDSLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | claimed |