Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3281773 | 0.87 | TSHR (0.43) | TSHRHPGD | |
| SCHEMBL11590481 | 0.85 | TSHR (0.39) | TSHRHPGDTHRBCTSK | |
| SCHEMBL11590360 | 0.83 | TSHR (0.38) | TSHRHPGDTHRBCTSK | |
| SCHEMBL5504190 | 0.81 | TSHR (0.41) | TSHRHPGDTHRBCTSK | |
| SCHEMBL11591610 | 0.81 | TSHR (0.43) | TSHRHPGDTHRBCTSK | |
| SCHEMBL11593256 | 0.80 | TSHR (0.39) | TSHRHPGDTHRBCTSK | |
| SCHEMBL1614909 | 0.79 | TSHR (0.38) | TSHRHPGDTHRB | |
| SCHEMBL3281067 | 0.78 | TSHR (0.47) | TSHRHPGD | |
| SCHEMBL16295832 | 0.77 | TSHR (0.38) | TSHRHPGDTHRBCTSK | |
| SCHEMBL11874447 | 0.74 | TSHR (0.37) | TSHRHPGDTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129610-A | VINYL COPOLYMER, EPOXY RESIN | HITACHI CHEMICAL CO., LTD. | 1978-12-12 | — | — | US | claimed |
| US-4163092-A | QUATERNIZED MONOMER, CROSS-LINKING AGENT | PLASTOMEDICAL SCIENCES, INC. (US) | 1979-07-31 | — | — | US | disclosed |
| US-4129610-A | VINYL COPOLYMER, EPOXY RESIN | HITACHI CHEMICAL CO., LTD. | 1978-12-12 | — | — | US | disclosed |
| US-4060678-A | Cationic hydrogels based on hydroxyalkyl acrylates and methacrylates | PLASTOMEDICAL SCIENCES, INC. (US) | 1977-11-29 | — | — | US | disclosed |
| US-4058491-A | Cationic hydrogels based on heterocyclic N-vinyl monomers | PLASTOMEDICAL SCIENCES, INC. (US) | 1977-11-15 | — | — | US | disclosed |