Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 8/20 | 0.45 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ADH1B | P00325 | 1/20 | 0.38 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | ADH7 | P40394 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522705 | 1.00 | RAD52 (0.47) | RAD52CXCR4CXCL12KDM4ECYP1A2 | |
| SCHEMBL17710342 | 0.97 | RAD52 (0.50) | RAD52CXCR4CXCL12KDM4EALDH1A1 | |
| SCHEMBL11522649 | 0.97 | RAD52 (0.50) | RAD52CXCR4CXCL12KDM4EALDH1A1 | |
| SCHEMBL4741840 | 0.97 | RAD52 (0.50) | RAD52CXCR4CXCL12KDM4EALDH1A1 | |
| SCHEMBL3298507 | 0.91 | RAD52 (0.52) | RAD52CXCR4CXCL12KDM4ECYP1A2 | |
| SCHEMBL20395033 | 0.88 | KDM4E (0.40) | RAD52CXCR4CXCL12KDM4EALDH1A1 | |
| SCHEMBL1779849 | 0.88 | RAD52 (0.56) | RAD52CXCR4CXCL12KDM4EALDH1A1 | |
| SCHEMBL10132045 | 0.88 | RAD52 (0.35) | RAD52CXCR4CXCL12ALDH1A1ADH1B | |
| SCHEMBL455085 | 0.88 | RAD52 (0.56) | RAD52CXCR4CXCL12KDM4EALDH1A1 | |
| SCHEMBL3795304 | 0.86 | CA12 (0.48) | RAD52CXCR4CXCL12KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179469-A | Preparation of amines | UOP INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4130715-A | Tricyclic trisaminomethanes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-12-19 | — | — | US | disclosed |
| US-4085106-A | Bicyclic and tricyclic trisaminomethanes | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1978-04-18 | — | — | US | disclosed |
| US-4038312-A | TRICYCLIC PHOSPHOROUS TRIAMIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-07-26 | — | — | US | disclosed |
| US-3996276-A | Bicyclic and tricyclic phosphorous triamides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-12-07 | — | — | US | disclosed |