Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28182817 | 0.80 | TDP1 (1.00) | TDP1ALDH1A1APPALOX5MAPT | |
| SCHEMBL5265446 | 0.78 | FNTA (0.39) | TDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL9367557 | 0.77 | TDP1 (0.92) | TDP1ALDH1A1APPALOX5MAPT | |
| SCHEMBL28562224 | 0.77 | KMT2A (0.60) | ALDH1A1MAPTKDM4EDAO | |
| SCHEMBL27807272 | 0.75 | TDP1 (0.89) | TDP1ALDH1A1APPALOX5MAPT | |
| Ammonia Solution, Strong SCHEMBL11481573 | 0.75 | TDP1 (0.89) | TDP1ALDH1A1APPALOX5MAPT | |
| SCHEMBL10602750 | 0.74 | GAA (0.57) | TDP1ALDH1A1MAPTKDM4E | |
| SCHEMBL6425149 | 0.74 | TDP1 (0.85) | TDP1ALDH1A1APPALOX5MAPT | |
| SCHEMBL2540241 | 0.74 | TDP1 (0.85) | TDP1ALDH1A1APPRXFP1ALOX5 | |
| SCHEMBL13583897 | 0.72 | TDP1 (0.82) | TDP1ALDH1A1APPALOX5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145556-A | N,N*-BIS(ALKYLHYDROXYPHENYL)ALKANOYLOXY-HYDROCARBYL)OXAMIDES | MONSANTO COMPANY (US) | 1979-03-20 | — | — | US | disclosed |