Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 7/20 | 0.72 |
| ▸ | RARB | P10826 | 4/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | PLA2G4B | P0C869 | 2/20 | 0.56 |
| ▸ | RARA | P10276 | 1/20 | 0.54 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8374334 | 0.99 | PTPN11 (0.70) | PTPN11RARBMCL1TP53TSHR | |
| SCHEMBL9650384 | 0.99 | PTPN11 (0.70) | PTPN11RARBMCL1TP53TSHR | |
| SCHEMBL9485391 | 0.99 | PTPN11 (0.70) | PTPN11RARBMCL1TP53TSHR | |
| SCHEMBL9485538 | 0.99 | PTPN11 (0.70) | PTPN11RARBMCL1TP53TSHR | |
| SCHEMBL9485471 | 0.99 | PTPN11 (0.70) | PTPN11RARBMCL1TP53TSHR | |
| SCHEMBL10340811 | 0.99 | PTPN11 (0.70) | PTPN11RARBMCL1TP53TSHR | |
| SCHEMBL9640138 | 0.99 | PTPN11 (0.70) | PTPN11RARBMCL1TP53TSHR | |
| SCHEMBL9486054 | 0.99 | PTPN11 (0.70) | PTPN11RARBMCL1TP53TSHR | |
| SCHEMBL7875556 | 0.99 | PTPN11 (0.70) | PTPN11RARBMCL1TP53TSHR | |
| SCHEMBL9484789 | 0.99 | PTPN11 (0.70) | PTPN11RARBMCL1TP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4147656-A | BIS(4'-N-OCTYLOXYBENZAL)-2-CHLORO-1,4-PHENYLENEDIAMINE, A SCHIFF BASE, \"LICRISTAL 9\ | ITEK CORPORATION (US) | 1979-04-03 | — | — | US | disclosed |
| US-4090975-A | BIS(4'-N-OCTYLOXYBENZAL)-2-CHLORO-1, 4-PHENYLENEDIAMINE | ITEK CORPORATION (US) | 1978-05-23 | — | — | US | disclosed |