Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.47 |
| ▸ | CA9 | Q16790 | 4/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523234 | 0.93 | KMT2A (0.57) | KMT2ANPC1CA1CA2CA9 | |
| SCHEMBL11522873 | 0.90 | KMT2A (0.61) | KMT2ANPC1CA1CA2CA9 | |
| SCHEMBL11521761 | 0.86 | NPC1 (0.53) | KMT2ANPC1CA1CA2CA9 | |
| SCHEMBL11523185 | 0.84 | KMT2A (0.63) | KMT2ANPC1CA1CA2CA9 | |
| SCHEMBL11520127 | 0.83 | KMT2A (0.50) | KMT2ANPC1CA1CA2CA9 | |
| SCHEMBL11522363 | 0.83 | KMT2A (0.58) | KMT2ANPC1CA1CA2CA9 | |
| SCHEMBL11522923 | 0.82 | NPC1 (0.56) | KMT2ANPC1CA1CA2CA9 | |
| SCHEMBL11520129 | 0.82 | KMT2A (0.60) | KMT2ANPC1CA1CA2CA9 | |
| SCHEMBL11522255 | 0.82 | NPC1 (0.51) | KMT2ANPC1CA1CA2CA9 | |
| SCHEMBL11456776 | 0.81 | CYP1A2 (0.46) | KMT2ACA1CA2CA9APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4176192-A | ANTHELMINTICS | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-11-27 | — | — | US | disclosed |