SCHEMBL11522971

SCHEMBL11522971

N=C(NCc1c[nH]cn1)NC(N)=O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL11527337 0.98
SCHEMBL11526675 0.85 MAPK1 (0.32)
Hydrochloric Acid SCHEMBL11524457 0.84 MAPK1 (0.31)
SCHEMBL11525286 0.83 HRH2 (0.32)
Oxalic Acid SCHEMBL11524306 0.79 HRH2 (0.32)
SCHEMBL20501735 0.75 SMN1; SMN2 (0.34)
SCHEMBL11525577 0.74
SCHEMBL18281971 0.74 SMN1; SMN2 (0.33)
SCHEMBL16136378 0.74 NPSR1 (0.50)
SCHEMBL16133692 0.73 MAPT (0.40)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4166860-A TREATMENT OF ACHLORHYDRIA AND DYSMENORRHEA WILLIAM H. RORER, INC. (US) 1979-09-04 US claimed
US-4166860-A TREATMENT OF ACHLORHYDRIA AND DYSMENORRHEA WILLIAM H. RORER, INC. (US) 1979-09-04 US disclosed