Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 5/20 | 0.44 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.44 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.37 |
| ▸ | HRH2 | P25021 | 2/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.37 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523115 | 1.00 | GRIA2 (0.44) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11618687 | 0.96 | GRIA1 (0.47) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11523214 | 0.90 | GRIA2 (0.43) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11523217 | 0.90 | GRIA2 (0.43) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11520101 | 0.87 | GRIA2 (0.47) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11520098 | 0.87 | GRIA2 (0.47) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11197639 | 0.86 | EGLN2 (0.38) | GRIA2GRIA1GRIA3HRH3HRH2 | |
| SCHEMBL11161506 | 0.86 | EGLN2 (0.38) | GRIA2GRIA1GRIA3HRH3HRH2 | |
| SCHEMBL11616336 | 0.85 | GRIA2 (0.45) | GRIA2GRIA1GRIA3HRH3KCNH2 | |
| SCHEMBL11194973 | 0.84 | ESR2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |