Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978384 | 0.82 | MAPT (0.63) | MAPTNPSR1ALDH1A1MAOBMEN1 | |
| SCHEMBL8464902 | 0.77 | MAPT (0.61) | MAPTNPSR1ALDH1A1MAOBMEN1 | |
| SCHEMBL8464899 | 0.77 | MAPT (0.61) | MAPTNPSR1ALDH1A1MAOBMEN1 | |
| SCHEMBL1373654 | 0.76 | MAPT (0.71) | MAPTNPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL11785708 | 0.74 | CYP3A4 (0.50) | MAPTNPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL12111897 | 0.74 | MAOB (0.59) | MAPTNPSR1ALDH1A1MAOBMEN1 | |
| SCHEMBL1149077 | 0.73 | CYP3A4 (0.55) | MAPTNPSR1ALDH1A1MEN1KMT2A | |
| SCHEMBL7829312 | 0.72 | MAPT (0.69) | MAPTNPSR1ALDH1A1MAOBMEN1 | |
| SCHEMBL7829304 | 0.72 | MAPT (0.69) | MAPTNPSR1ALDH1A1MAOBMEN1 | |
| SCHEMBL8219793 | 0.72 | MEN1 (0.64) | MAPTNPSR1ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4179500-A | 1,4-Dihydropyridine-sugar derivatives, and their use as medicaments | BAYER AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |