Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.61 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.56 |
| ▸ | CTDSP1 | Q9GZU7 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.56 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.56 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.56 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | KDR | P35968 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11416312 | 1.00 | PTGS1 (0.69) | PTGS1L3MBTL1TDP1MAPTNR1I2 | |
| SCHEMBL11691157 | 0.94 | PTGS1 (0.60) | PTGS1L3MBTL1TDP1MAPTNR1I2 | |
| SCHEMBL11691159 | 0.93 | PTGS1 (0.61) | PTGS1L3MBTL1TDP1MAPTNR1I2 | |
| SCHEMBL11275658 | 0.90 | PTGS1 (0.74) | PTGS1L3MBTL1TDP1MAPTNR1I2 | |
| SCHEMBL11146919 | 0.89 | PTGS1 (0.78) | PTGS1L3MBTL1TDP1MAPTNR1I2 | |
| SCHEMBL11275281 | 0.89 | PTGS1 (0.62) | PTGS1L3MBTL1TDP1MAPTNR1I2 | |
| SCHEMBL11695138 | 0.88 | PTGS1 (0.55) | PTGS1L3MBTL1TDP1MAPTNR1I2 | |
| SCHEMBL11692348 | 0.88 | PTGS1 (0.54) | PTGS1L3MBTL1TDP1MAPTNR1I2 | |
| SCHEMBL11280018 | 0.87 | PTGS1 (0.60) | PTGS1L3MBTL1TDP1MAPTNR1I2 | |
| SCHEMBL11634916 | 0.87 | PTGS1 (0.66) | PTGS1L3MBTL1TDP1MAPTNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | claimed |
| US-4144391-A | REPLACING AN ACETOXY GROUP BY A SULFUR NUCLEOPHILE | ELI LILLY AND COMPANY (US) | 1979-03-13 | — | — | US | disclosed |