Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.66 |
| ▸ | MEN1 | O00255 | 9/20 | 0.66 |
| ▸ | MAPT | P10636 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PHGDH | O43175 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MITF | O75030 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALPL | P05186 | 1/20 | 0.43 |
| ▸ | ALPG | P10696 | 1/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16355193 | 0.88 | MAPT (0.52) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL14132237 | 0.87 | MAPT (0.52) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL9816832 | 0.87 | KMT2A (0.66) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL28985487 | 0.86 | KMT2A (0.50) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL28985486 | 0.86 | KMT2A (0.50) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL10184550 | 0.85 | MAPT (0.65) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL15137876 | 0.84 | KMT2A (0.61) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL11525052 | 0.83 | MAPT (0.55) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL23219644 | 0.82 | KMT2A (0.57) | KMT2AMEN1MAPTALDH1A1PKM | |
| SCHEMBL12694051 | 0.82 | MAPT (0.48) | KMT2AMEN1MAPTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134723-A | DYEING AROMATIC POLYESTER/POLYAMIDE OR AROMATIC POLYESTER/CELLULOSE BLENDS WITH DISPERSE MONOAZO DYE, ALKALINE BATH | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1979-01-16 | — | — | US | disclosed |