Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HRH2 | P25021 | 2/20 | 0.40 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.39 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11523764 | 1.00 | TSHR (0.51) | TSHRHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL11523768 | 1.00 | TSHR (0.51) | TSHRHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL11525037 | 1.00 | TSHR (0.51) | TSHRHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL11524189 | 1.00 | TSHR (0.51) | TSHRHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL11527389 | 1.00 | TSHR (0.51) | TSHRHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL11527385 | 1.00 | TSHR (0.51) | TSHRHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL9632203 | 1.00 | TSHR (0.51) | TSHRHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL11524192 | 1.00 | TSHR (0.51) | TSHRHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL11524002 | 1.00 | TSHR (0.51) | TSHRHSD17B10MEN1KMT2AMAPK1 | |
| SCHEMBL5953093 | 1.00 | TSHR (0.51) | TSHRHSD17B10MEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |