Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.76 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 2/20 | 0.76 |
| ▸ | TP53 | P04637 | 2/20 | 0.76 |
| ▸ | GMNN | O75496 | 1/20 | 0.76 |
| ▸ | POLB | P06746 | 1/20 | 0.76 |
| ▸ | THPO | P40225 | 1/20 | 0.76 |
| ▸ | MTOR | P42345 | 1/20 | 0.76 |
| ▸ | BLM | P54132 | 1/20 | 0.76 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | CETP | P11597 | 1/20 | 0.76 |
| ▸ | HTT | P42858 | 1/20 | 0.76 |
| ▸ | UBE2N | P61088 | 1/20 | 0.76 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.58 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.52 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11524107 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL11524277 | 1.00 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL6118549 | 0.95 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL6117945 | 0.95 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL16859679 | 0.95 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL16104483 | 0.95 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL6118606 | 0.95 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL16859677 | 0.95 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL6118653 | 0.95 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN | |
| SCHEMBL16859681 | 0.95 | CYP2D6 (0.76) | CYP2D6SPHK1LMNATP53GMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140860-A | BACTERICIDES | STERLING DRUG INC. (US) | 1979-02-20 | — | — | US | disclosed |
| US-4119668-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1978-10-10 | — | — | US | disclosed |
| US-4085144-A | ANTIBACTERIAL | STERLING DRUG INC. (US) | 1978-04-18 | — | — | US | disclosed |
| US-4022833-A | ANTIBACTERIAL AGENTS | STERLING DRUG INC. (US) | 1977-05-10 | — | — | US | disclosed |