Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311068 | 0.89 | ESR1 (0.35) | ESR1TSHRKMT2ALMNAL3MBTL1 | |
| SCHEMBL313673 | 0.77 | KMT2A (0.49) | ESR1TSHRKMT2ALMNAL3MBTL1 | |
| SCHEMBL21163248 | 0.75 | GAA (0.32) | ESR1TSHRKMT2ALMNAL3MBTL1 | |
| SCHEMBL11526398 | 0.75 | KMT2A (0.42) | ESR1TSHRKMT2ALMNAL3MBTL1 | |
| SCHEMBL11527304 | 0.75 | KMT2A (0.42) | ESR1TSHRKMT2ALMNAL3MBTL1 | |
| SCHEMBL11525453 | 0.75 | KMT2A (0.42) | ESR1TSHRKMT2ALMNAL3MBTL1 | |
| SCHEMBL11284335 | 0.74 | ESR1 (0.32) | ESR1TSHRKMT2ALMNAL3MBTL1 | |
| SCHEMBL11526815 | 0.74 | ESR1 (0.32) | ESR1TSHRKMT2ALMNAL3MBTL1 | |
| SCHEMBL14394447 | 0.74 | ESR1 (0.32) | ESR1TSHRKMT2ALMNAL3MBTL1 | |
| SCHEMBL11526339 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4177186-A | 4-SILOXY-DERIVATIVES OF STERICALLY HINDERED PIPERIDINES | CIBA-GEIGY CORPORATION (US) | 1979-12-04 | — | — | US | disclosed |