SCHEMBL11526451

SCHEMBL11526451

O=C(O)C(c1cccc(F)c1)[N+](=O)[O-]

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
CES2 O00748 2/20 0.45
CES1 P23141 2/20 0.45
CNR2 P34972 1/20 0.42
PGR P06401 1/20 0.40
AR P10275 1/20 0.40
EPHX1 P07099 1/20 0.40
CNR1 P21554 1/20 0.40
FBP1 P09467 2/20 0.40
IDO1 P14902 1/20 0.39
TDO2 P48775 1/20 0.39
MTOR P42345 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28005114 0.81 HDAC4 (0.45) HDAC4HDAC7HDAC5CES2CES1
SCHEMBL6106703 0.80 ACP3 (0.45) EPHX1CNR1FBP1
SCHEMBL6100121 0.80 MEN1 (0.47) CNR1FBP1
SCHEMBL74691 0.80 SRC (0.48) CES2CES1
SCHEMBL27810151 0.79 HDAC3 (0.40) HDAC4HDAC7HDAC5CES2CES1
SCHEMBL11602886 0.78 SRC (0.46) CES2CES1
SCHEMBL887039 0.78 SRC (0.46) CES2CES1
SCHEMBL11602507 0.78 SRC (0.46) CES2CES1
SCHEMBL27814338 0.78 PTGS1 (0.58)
SCHEMBL3711116 0.74 SRC (0.58) HDAC4HDAC7HDAC5CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104447347-A Preparation method for sunitinibmalate intermediate PARLING SHANGHAI PHARMATECH CO LTD 2015-03-25 CN claimed
WO-2026098560-A2 BENZENE-CONTAINING POLYCYCLIC DERIVATIVE MODULATOR, PREPARATION METHOD THEREFOR AND USE THEREOF 上海翰森生物医药科技有限公司 2026-05-15 WO disclosed
CN-110551103-B JAK3 selective inhibitor 北京大学深圳研究生院 2022-08-23 CN disclosed
CN-110551103-A JAK3 selective inhibitor SHENZHEN GRADUATE SCHOOL PEKING UNIV 2019-12-10 CN disclosed
CN-104447347-A Preparation method for sunitinibmalate intermediate PARLING SHANGHAI PHARMATECH CO LTD 2015-03-25 CN disclosed
CN-104447347-A Preparation method for sunitinibmalate intermediate PARLING SHANGHAI PHARMATECH CO LTD 2015-03-25 CN disclosed
US-4160032-A Oxindoles as sleep-inducers SANDOZ, INC. (US) 1979-07-03 US disclosed