Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.41 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.37 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.37 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.37 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10001904 | 0.98 | AURKA (0.47) | AURKAAURKBCTRB1CYP1A2TTR | |
| SCHEMBL3822788 | 0.90 | AURKA (0.42) | AURKAAURKBCTRB1CYP1A2TTR | |
| SCHEMBL29623330 | 0.90 | AURKA (0.50) | AURKAAURKBCTRB1CYP1A2TTR | |
| SCHEMBL29825144 | 0.90 | AURKA (0.50) | AURKAAURKBCTRB1CYP1A2TTR | |
| SCHEMBL139959 | 0.90 | AURKA (0.50) | AURKAAURKBCTRB1CYP1A2TTR | |
| SCHEMBL30218795 | 0.90 | AURKA (0.42) | AURKAAURKBCTRB1CYP1A2TTR | |
| SCHEMBL28203347 | 0.90 | AURKA (0.50) | AURKAAURKBCTRB1CYP1A2TTR | |
| Water SCHEMBL14688267 | 0.88 | AURKA (0.49) | AURKAAURKBCTRB1CYP1A2TTR | |
| SCHEMBL592126 | 0.88 | AURKA (0.49) | AURKAAURKBCTRB1CYP1A2TTR | |
| SCHEMBL592128 | 0.88 | AURKA (0.49) | AURKAAURKBCTRB1CYP1A2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136229-A | SECURITY PAPER | SOCIETE ANONYME DITE: ARJOMARI-PRIOUX (FR) | 1979-01-23 | — | — | US | disclosed |