Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11529812 | 1.00 | IDH1 (0.38) | IDH1TDP1HTT | |
| SCHEMBL9489812 | 1.00 | IDH1 (0.38) | IDH1TDP1HTT | |
| SCHEMBL9691412 | 0.81 | — | — | |
| SCHEMBL10585806 | 0.80 | IDH1 (0.35) | IDH1 | |
| SCHEMBL10585803 | 0.80 | IDH1 (0.35) | IDH1 | |
| SCHEMBL11959956 | 0.79 | TDP1 (0.53) | IDH1TDP1HTT | |
| SCHEMBL28105948 | 0.78 | IDH1 (0.46) | IDH1 | |
| SCHEMBL9489809 | 0.76 | IDH1 (0.38) | IDH1TDP1HTT | |
| SCHEMBL8321135 | 0.74 | IDH1 (0.40) | IDH1TDP1 | |
| SCHEMBL7536857 | 0.74 | IDH1 (0.40) | IDH1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4171355-A | COMPRISING A CYCLOPROPYL CARBOXYLATE, A HETERO N-SUBSTITUTED THIOPHOSPHATE COMPOUND AND A HYDROXY-SUBSTITUTED BENZOPHENONE | ICI AUSTRALIA LIMITED (AU) | 1979-10-16 | — | — | US | disclosed |