Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.49 |
| ▸ | HRH2 | P25021 | 4/20 | 0.49 |
| ▸ | HRH1 | P35367 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | MGLL | Q99685 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11522571 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL11528760 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL11523279 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL11522578 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL11522183 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL11522180 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL11524715 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL11524710 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL11523273 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDHTTL3MBTL1 | |
| SCHEMBL11527311 | 0.99 | KDM4E (0.52) | KDM4EALDH1A1HPGDHTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154697-A | Liquid crystalline hexahydroterphenyl derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1979-05-15 | — | — | US | disclosed |