Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | HTT | P42858 | 3/20 | 0.36 |
| ▸ | UBE2N | P61088 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 2/20 | 0.34 |
| ▸ | STAT3 | P40763 | 1/20 | 0.34 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.34 |
| ▸ | APAF1 | O14727 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7704204 | 0.94 | NPSR1 (0.40) | NPSR1KMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL11754837 | 0.90 | NPSR1 (0.40) | NPSR1KMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL11421800 | 0.89 | MAPK1 (0.39) | NPSR1KMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL11647481 | 0.88 | MAPK1 (0.37) | NPSR1KMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL11877719 | 0.88 | NPSR1 (0.41) | NPSR1KMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL3429177 | 0.87 | KMT2A (0.39) | NPSR1KMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL11757359 | 0.87 | MAPK1 (0.38) | NPSR1KMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL8075435 | 0.86 | MAPK1 (0.39) | NPSR1KMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL11513749 | 0.86 | ACACB (0.37) | NPSR1KMT2AMAPK1MEN1SMN1; SMN2 | |
| SCHEMBL9814162 | 0.86 | KMT2A (0.40) | NPSR1KMT2AMAPK1MEN1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134770-A | VINYLSULFONYLPROPIONYL COMPOUNDS | MITSUBISHI PAPER MILLS, LTD. (JP) | 1979-01-16 | — | — | US | disclosed |