Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12714714 | 1.00 | TDP1 (0.61) | TDP1CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL11529209 | 1.00 | TDP1 (0.61) | TDP1CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL15769635 | 0.98 | TDP1 (0.64) | TDP1 | |
| SCHEMBL15783533 | 0.98 | TDP1 (0.64) | TDP1 | |
| SCHEMBL15783527 | 0.98 | TDP1 (0.64) | TDP1 | |
| SCHEMBL6393609 | 0.98 | TDP1 (0.64) | TDP1 | |
| SCHEMBL15783526 | 0.98 | TDP1 (0.64) | TDP1 | |
| Hydrochloric Acid SCHEMBL16143332 | 0.96 | TDP1 (0.62) | TDP1 | |
| SCHEMBL12714711 | 0.95 | TDP1 (0.55) | TDP1CYP2D6MEN1KMT2ALMNA | |
| SCHEMBL12714722 | 0.93 | TDP1 (0.53) | TDP1CYP2D6MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145435-A | 2-AMINOCYCLOALIPHATIC AMIDE COMPOUNDS | THE UPJOHN COMPANY (US) | 1979-03-20 | — | — | US | disclosed |