Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11616340 | 0.84 | MAPK1 (0.56) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL10930709 | 0.83 | MAPK1 (0.51) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL11016129 | 0.81 | MAPK1 (0.49) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL11535132 | 0.81 | MAPK1 (0.40) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL11014346 | 0.79 | MAPK1 (0.46) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL9858894 | 0.78 | MAPK1 (0.61) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL11079871 | 0.77 | MAPK1 (0.56) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL2789021 | 0.77 | MAPK1 (0.56) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL11529569 | 0.77 | MAPK1 (0.56) | MAPK1TDP1CYP3A4TSHRTRPA1 | |
| SCHEMBL11531112 | 0.76 | MAPK1 (0.54) | MAPK1TDP1CYP3A4TSHRTRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140792-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |