Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 3/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11863879 | 1.00 | TSHR (0.44) | TSHRALDH1A1LMNADNM1ADH1B | |
| SCHEMBL24784724 | 0.85 | TSHR (0.43) | TSHRALDH1A1LMNADNM1ADH1B | |
| SCHEMBL1137443 | 0.83 | TSHR (0.41) | TSHRALDH1A1LMNADNM1ADH1B | |
| SCHEMBL24785613 | 0.83 | TSHR (0.41) | TSHRALDH1A1LMNADNM1ADH1B | |
| Hydrochloric Acid SCHEMBL6705010 | 0.82 | TSHR (0.32) | TSHR | |
| SCHEMBL3806771 | 0.82 | TSHR (0.40) | TSHRLMNAPLA2G1BFDPSGPR84 | |
| Hydrochloric Acid SCHEMBL28838225 | 0.82 | TSHR (0.40) | TSHRALDH1A1LMNADNM1ADH1B | |
| Bromide SCHEMBL28902969 | 0.82 | TSHR (0.40) | TSHRALDH1A1LMNADNM1ADH1B | |
| Hydrochloric Acid SCHEMBL11680488 | 0.82 | TSHR (0.40) | TSHRALDH1A1LMNADNM1ADH1B | |
| Hydrochloric Acid SCHEMBL11303952 | 0.82 | TSHR (0.40) | TSHRALDH1A1LMNADNM1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4139499-A | Thermally reversible amphoteric ion exchange resins of improved demineralization capacity | ICI AUSTRALIA LIMITED (AU) | 1979-02-13 | — | — | US | disclosed |