Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GLI1 | P08151 | 1/20 | 0.45 |
| ▸ | GLI2 | P10070 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | EPOR | P19235 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11742132 | 0.85 | PTGS1 (0.51) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL11534559 | 0.84 | PTGS1 (0.54) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL11533828 | 0.82 | PTGS1 (0.53) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL11539169 | 0.81 | PTGS1 (0.52) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL11534785 | 0.81 | PTGS1 (0.61) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL11141447 | 0.80 | PTGS1 (0.65) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL11138445 | 0.78 | PTGS1 (0.63) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL11145407 | 0.77 | PTGS1 (0.61) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL11531884 | 0.77 | PTGS1 (0.61) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL11531592 | 0.76 | PTGS1 (0.60) | PTGS1ALOX5MEN1CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145557-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4062895-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | ELI LILLY AND COMPANY (US) | 1977-12-13 | — | — | US | disclosed |
| US-4001322-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3972934-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |