Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.30 |
| ▸ | HTR3B | O95264 | 1/20 | 0.30 |
| ▸ | HTR3A | P46098 | 1/20 | 0.30 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.30 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11532906 | 0.81 | TDP1 (0.36) | CYP3A4MAPK1TDP1 | |
| SCHEMBL11526274 | 0.78 | TDP1 (0.34) | CYP3A4MAPK1TDP1 | |
| SCHEMBL3548255 | 0.78 | CYP3A4 (0.50) | CYP3A4KMT2AGABRA1GABRB2MAPK1 | |
| SCHEMBL11531900 | 0.77 | CYP3A4 (0.42) | CYP3A4KMT2AGABRA1GABRB2MAPK1 | |
| SCHEMBL7930996 | 0.76 | KMT2A (0.52) | KMT2A | |
| SCHEMBL11603241 | 0.74 | CYP3A4 (0.42) | CYP3A4KMT2ATDP1HTR3EHTR3B | |
| SCHEMBL6528300 | 0.73 | CYP3A4 (0.42) | CYP3A4GABRA1GABRB2TDP1 | |
| SCHEMBL7534773 | 0.72 | CYP3A4 (0.56) | CYP3A4KMT2AGABRA1GABRB2MAPK1 | |
| SCHEMBL163526 | 0.72 | CYP3A4 (0.50) | CYP3A4KMT2AGABRA1GABRB2MAPK1 | |
| SCHEMBL27609930 | 0.71 | CYP3A4 (0.46) | CYP3A4KMT2AGABRA1GABRB2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4140792-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-20 | — | — | US | disclosed |