Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.56 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.56 |
| ▸ | PGR | P06401 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.56 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.56 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11479945 | 0.97 | KCNH2 (0.59) | KCNH2SLC22A2SLC22A1PGRTHRB | |
| Hydrochloric Acid SCHEMBL11535326 | 0.95 | KCNH2 (0.57) | KCNH2SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL11532073 | 0.92 | KCNH2 (0.54) | KCNH2SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL11532105 | 0.92 | KCNH2 (0.54) | KCNH2SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL11531340 | 0.89 | CYP3A4 (0.52) | KCNH2SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL11478525 | 0.89 | KCNH2 (0.51) | KCNH2SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL11535491 | 0.88 | KCNH2 (0.51) | KCNH2SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL11536300 | 0.88 | KCNH2 (0.51) | KCNH2SLC22A2SLC22A1PGRTHRB | |
| Hydrochloric Acid SCHEMBL11487983 | 0.87 | KCNH2 (0.50) | KCNH2SLC22A2SLC22A1PGRTHRB | |
| SCHEMBL11480975 | 0.85 | KCNH2 (0.51) | KCNH2SLC22A2SLC22A1PGRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153797-A | α-Aryl-α, α-bis[ω- (disubstituted amino)alkyl]acetamides and related compounds | G. D. SEARLE & CO. (US) | 1979-05-08 | — | — | US | disclosed |
| US-4107205-A | α-Aryl-α,α-bis[ω-(disubstituted amino)alkyl]acetamides and related compounds | G. D. SEARLE & CO. (US) | 1978-08-15 | — | — | US | disclosed |