Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | GLI1 | P08151 | 1/20 | 0.42 |
| ▸ | GLI2 | P10070 | 1/20 | 0.42 |
| ▸ | FAAH | O00519 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11532693 | 0.98 | TAAR1 (0.58) | TAAR1PTGS1ALOX5MEN1CYP2D6 | |
| Hydrochloric Acid SCHEMBL11536745 | 0.85 | PTGS1 (0.53) | TAAR1PTGS1ALOX5MEN1CYP2D6 | |
| SCHEMBL11996670 | 0.84 | PTGS1 (0.58) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL11534785 | 0.83 | PTGS1 (0.61) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL4048471 | 0.83 | PTGS1 (0.57) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| SCHEMBL13886663 | 0.82 | HTR2A (0.59) | TAAR1PTGS1ALOX5MEN1CYP2D6 | |
| SCHEMBL410128 | 0.82 | TAAR1 (0.53) | TAAR1 | |
| SCHEMBL413321 | 0.82 | TAAR1 (0.53) | TAAR1 | |
| SCHEMBL27629422 | 0.81 | PTGS1 (0.55) | PTGS1ALOX5MEN1CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL4449389 | 0.81 | HTR2A (0.57) | TAAR1PTGS1ALOX5MEN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4145557-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, ANTIPYRETICS | ELI LILLY AND COMPANY (US) | 1979-03-20 | — | — | US | disclosed |
| US-4062895-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | ELI LILLY AND COMPANY (US) | 1977-12-13 | — | — | US | disclosed |
| US-4001322-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | ELI LILLY AND COMPANY (US) | 1977-01-04 | — | — | US | disclosed |
| US-3972934-A | ANTIINFLAMMATORY, ANALGESIC, ANTIPYRETIC | ELI LILLY AND COMPANY (US) | 1976-08-03 | — | — | US | disclosed |