Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11534361 | 1.00 | SMN1; SMN2 (0.49) | SMN1; SMN2RAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL11537721 | 0.88 | MAPT (0.45) | SMN1; SMN2RAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL11537720 | 0.88 | MAPT (0.45) | SMN1; SMN2RAB9ANPC1POLBL3MBTL1 | |
| Bromide SCHEMBL11530395 | 0.87 | MAPT (0.44) | SMN1; SMN2RAB9ANPC1POLBL3MBTL1 | |
| Bromide SCHEMBL11530387 | 0.87 | MAPT (0.44) | SMN1; SMN2RAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL11545041 | 0.80 | GAA (0.49) | SMN1; SMN2RAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL11545038 | 0.80 | GAA (0.49) | SMN1; SMN2RAB9ANPC1POLBL3MBTL1 | |
| SCHEMBL11532623 | 0.77 | KMT2A (0.54) | SMN1; SMN2RAB9ANPC1POLBMEN1 | |
| SCHEMBL11532626 | 0.77 | KMT2A (0.54) | SMN1; SMN2RAB9ANPC1POLBMEN1 | |
| SCHEMBL11530907 | 0.75 | TSHR (0.39) | SMN1; SMN2L3MBTL1KMT2AHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4154733-A | INSECTICIDES, MITICIDES, NEMATOCIDES | DIAMOND SHAMROCK CORPORATION (US) | 1979-05-15 | — | — | US | claimed |
| US-4156082-A | INSECTICIDES, MITICIDES, NEMATOCIDES | DIAMOND SHAMROCK CORPORATION (US) | 1979-05-22 | — | — | US | disclosed |
| US-4154732-A | INSECTICIDES, MITICIDES, NEMATOCIDES | DIAMOND SHAMROCK CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154733-A | INSECTICIDES, MITICIDES, NEMATOCIDES | DIAMOND SHAMROCK CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154944-A | INSECTICIDES, MITICIDES, NEMATOCIDES | DIAMOND SHAMROCK CORPORATION (US) | 1979-05-15 | — | — | US | disclosed |
| US-4118389-A | INSECTICIDES, MITICIDES, NEMATOCIDES | DIAMOND SHAMROCK CORPORATION (US) | 1978-10-03 | — | — | US | disclosed |