Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.37 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540015 | 0.99 | KMT2A (0.42) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11533194 | 0.85 | KMT2A (0.54) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11533715 | 0.84 | KMT2A (0.53) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11539389 | 0.81 | KMT2A (0.48) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11536188 | 0.80 | CYP19A1 (0.41) | KMT2ACYP19A1 | |
| SCHEMBL11531936 | 0.78 | MEN1 (0.48) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL9271702 | 0.77 | MAPT (0.37) | KMT2AALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1347394 | 0.76 | KMT2A (0.54) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 | |
| SCHEMBL11534499 | 0.76 | KCNH2 (0.40) | KMT2AMEN1ALDH1A1CYP19A1NPSR1 | |
| SCHEMBL11537049 | 0.76 | KMT2A (0.45) | KMT2AMEN1ALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4152441-A | Analgesic imidazolemethanols | GIST-BROCADES N.V. (NL) | 1979-05-01 | — | — | US | disclosed |