Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 10/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19813197 | 0.76 | EPHX2 (0.42) | KDM4ETDP1ALDH1A1PKMTSHR | |
| SCHEMBL11802476 | 0.74 | EPHX2 (0.47) | KDM4ETDP1ALDH1A1PKMKMT2A | |
| SCHEMBL23194499 | 0.73 | KDM4E (0.43) | KDM4ETDP1ALDH1A1PKMTSHR | |
| SCHEMBL11332760 | 0.72 | KDM4E (0.46) | KDM4ETDP1ALDH1A1PKMKMT2A | |
| SCHEMBL1142727 | 0.71 | TDP1 (0.42) | KDM4ETDP1ALDH1A1PKMKMT2A | |
| SCHEMBL26528114 | 0.71 | EPHX2 (0.41) | KDM4ETDP1ALDH1A1KMT2A | |
| SCHEMBL11541368 | 0.71 | PTGIR (0.47) | PTGIR | |
| SCHEMBL11540389 | 0.71 | KDM4E (0.40) | KDM4ETDP1ALDH1A1PKMKMT2A | |
| SCHEMBL11540386 | 0.71 | KDM4E (0.40) | KDM4ETDP1ALDH1A1PKMKMT2A | |
| SCHEMBL11797284 | 0.71 | KDM4E (0.43) | KDM4ETDP1ALDH1A1PKMKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136180-A | HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4062960-A | Hypolipidemic alkenesulfonamides | PFIZER INC. (US) | 1977-12-13 | — | — | US | disclosed |
| US-4052507-A | HYPOGLYCEMIC | PFIZER INC. (US) | 1977-10-04 | — | — | US | disclosed |
| US-3998828-A | ORAL HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1976-12-21 | — | — | US | disclosed |
| US-3987172-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1976-10-19 | — | — | US | disclosed |
| US-3983107-A | ARTERIOSCLEROSIS | PFIZER INC. (US) | 1976-09-28 | — | — | US | disclosed |
| US-3961067-A | Composition comprising a benzenesulfonylurea hypoglycemic agent and method of treatment | PFIZER INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3961065-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1976-06-01 | — | — | US | disclosed |
| US-3944524-A | ORAL HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1976-03-16 | — | — | US | disclosed |
| US-3936455-A | ORAL HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1976-02-03 | — | — | US | disclosed |