Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11535724 | 1.00 | KDM4E (0.37) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11541129 | 0.80 | KDM4E (0.39) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11541126 | 0.80 | KDM4E (0.39) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11540386 | 0.79 | KDM4E (0.40) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11540389 | 0.79 | KDM4E (0.40) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11539066 | 0.78 | SLC6A4 (0.35) | KDM1A | |
| SCHEMBL11539064 | 0.78 | SLC6A4 (0.35) | KDM1A | |
| SCHEMBL11539087 | 0.78 | KDM4E (0.39) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11539089 | 0.78 | KDM4E (0.39) | KDM4ETDP1PKMALDH1A1KMT2A | |
| SCHEMBL11537232 | 0.75 | KDM4E (0.39) | KDM4ETDP1PKMALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4136180-A | HYPOLIPIDEMIC SUBSTITUTED STYRENESULFONYLUREAS | PFIZER INC. (US) | 1979-01-23 | — | — | US | disclosed |
| US-4062960-A | Hypolipidemic alkenesulfonamides | PFIZER INC. (US) | 1977-12-13 | — | — | US | disclosed |