SCHEMBL11536288

SCHEMBL11536288

COCCCN(Cc1nc2ccccc2[nH]1)Cc1nc2ccccc2[nH]1

nearest known ligand 0.70

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.70
POLB P06746 2/20 0.50
HSD17B10 Q99714 2/20 0.50
DDAH1 O94760 1/20 0.50
KDM4E B2RXH2 2/20 0.48
ALDH1A1 P00352 2/20 0.48
TDP1 Q9NUW8 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
NPC1 O15118 2/20 0.47
RAB9A P51151 2/20 0.47
MAPT P10636 1/20 0.47
ATP4A P20648 1/20 0.46
ATP4B P51164 1/20 0.46
PKM P14618 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20677816 0.87 BCHE (0.87) BCHEPOLBDDAH1TDP1SMN1; SMN2
SCHEMBL20677807 0.87 BCHE (0.87) BCHEPOLBDDAH1TDP1SMN1; SMN2
SCHEMBL8201381 0.83 BCHE (1.00) BCHEPOLBDDAH1TDP1SMN1; SMN2
SCHEMBL709151 0.82 BCHE (0.72) BCHEPOLBDDAH1ALDH1A1TDP1
SCHEMBL5138617 0.81 BCHE (0.70) BCHEPOLBDDAH1ALDH1A1TDP1
SCHEMBL29550341 0.80 BCHE (0.86) BCHEPOLBDDAH1TDP1SMN1; SMN2
SCHEMBL370724 0.80 BCHE (0.86) BCHEPOLBDDAH1TDP1SMN1; SMN2
Hydrochloric Acid SCHEMBL709234 0.80 BCHE (0.68) BCHEPOLBDDAH1ALDH1A1TDP1
Hydrochloric Acid SCHEMBL709235 0.80 BCHE (0.68) BCHEPOLBDDAH1ALDH1A1TDP1
SCHEMBL20677805 0.79 BCHE (0.72) BCHEPOLBDDAH1TDP1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4177155-A N-AMINOMETHYL-TRIAZOLES AND IMIDAZOLES FOR MAKING ANTIFREEZES NONCORROSIVE CIBA-GEIGY CORPORATION (US) 1979-12-04 US disclosed