Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 2/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10909271 | 0.90 | CES1 (0.50) | HTR1ALMNAPOLBMAP2K1CES1 | |
| Pyroquilon SCHEMBL22234 | 0.76 | MAP2K1 (0.55) | CA12CA1CA2CA4CA7 | |
| Pyroquilon SCHEMBL29473240 | 0.76 | MAP2K1 (0.55) | CA12CA1CA2CA4CA7 | |
| Pyroquilon SCHEMBL8820252 | 0.76 | MAP2K1 (0.55) | CA12CA1CA2CA4CA7 | |
| Pyroquilon SCHEMBL29473172 | 0.74 | MAP2K1 (0.54) | CA12CA1CA2CA4CA7 | |
| Pyroquilon SCHEMBL19409911 | 0.74 | MAP2K1 (0.54) | CA12CA1CA2CA4CA7 | |
| SCHEMBL31649829 | 0.73 | CES1 (0.49) | CA12CA1CA2CA4CA7 | |
| Pyroquilon SCHEMBL29473298 | 0.73 | MAP2K1 (0.53) | CA12CA1CA2CA4CA7 | |
| SCHEMBL7247820 | 0.73 | CES1 (0.49) | CA12CA1CA2CA4CA7 | |
| Pyroquilon SCHEMBL29473299 | 0.73 | MAP2K1 (0.53) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4133954-A | FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1979-01-09 | — | — | US | claimed |
| US-4133954-A | FUNGICIDES | CIBA-GEIGY CORPORATION (US) | 1979-01-09 | — | — | US | disclosed |