SCHEMBL11536798

SCHEMBL11536798

CC(Cl)C(=O)OCC(C)(C)C(=O)C(Br)Oc1ccc(Cl)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIN2D O15399 1/20 0.42
GRIN3B O60391 1/20 0.42
GRIN1 Q05586 1/20 0.42
GRIN2A Q12879 1/20 0.42
GRIN2B Q13224 1/20 0.42
GRIN2C Q14957 1/20 0.42
GRIN3A Q8TCU5 1/20 0.42
GAA P10253 2/20 0.39
NPSR1 Q6W5P4 1/20 0.39
GPR55 Q9Y2T6 1/20 0.39
CYP3A4 P08684 6/20 0.38
PPARA Q07869 6/20 0.38
CYP1A2 P05177 4/20 0.38
PMP22 Q01453 2/20 0.38
ABCB11 O95342 1/20 0.38
TSHR P16473 1/20 0.38
HTR2A P28223 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
ADORA3 P0DMS8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11461141 0.87 PPARA (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11536839 0.86 ELANE (0.43) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11541146 0.85 PPARA (0.41) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11540833 0.85 PPARA (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11533658 0.85 GAA (0.40) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL10916454 0.84 SSTR4 (0.45) GAANPSR1GPR55CYP3A4PPARA
SCHEMBL11536505 0.84 GAA (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11536914 0.84 CYP1A2 (0.38) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11537963 0.84 PPARA (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL11537279 0.84 GRIN2D (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4154842-A Fungicidally and bactericidally active 1-azolyl-4-hydroxy-1-phenoxy-butane derivatives BAYER AKTIENGESELLSCHAFT (DE) 1979-05-15 US disclosed