SCHEMBL11537489

SCHEMBL11537489

C=CCON=C(C)OCC

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TSHR P16473 1/20 0.32
LMNA P02545 2/20 0.31
ALDH1A1 P00352 1/20 0.31
HSD17B10 Q99714 1/20 0.31
MAPT P10636 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11537485 1.00 KMT2A (0.32) KMT2ASMN1; SMN2TSHRLMNAALDH1A1
SCHEMBL755637 0.82
SCHEMBL755638 0.82
SCHEMBL11037871 0.75
SCHEMBL6036828 0.75
SCHEMBL12073563 0.74
SCHEMBL11038502 0.74
SCHEMBL28324021 0.71 MAPT (0.32) KMT2ASMN1; SMN2TSHRLMNAALDH1A1
SCHEMBL27017038 0.71
SCHEMBL18914928 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4150043-A 0-(2,3-Epoxypropyl)-hydroximic acid esters HOECHST AKTIENGESELLSCHAFT (DE) 1979-04-17 US disclosed