SCHEMBL11538167

SCHEMBL11538167

O=C(O)c1ccc2sc(=O)[nH]c(=O)c2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 4/20 0.46
CSNK2A1 P68400 4/20 0.46
CSNK2A2 P19784 1/20 0.46
CSNK2B P67870 1/20 0.46
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 1/20 0.45
THRB P10828 1/20 0.45
HPGD P15428 1/20 0.45
STS P08842 1/20 0.44
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
RECQL P46063 1/20 0.41
CYP1A2 P05177 1/20 0.40
MAT2A P31153 1/20 0.39
KIF11 P52732 1/20 0.39
GRIK1 P39086 1/20 0.38
GRIK2 Q13002 1/20 0.38
GRIK3 Q13003 1/20 0.38
TBXAS1 P24557 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11541325 0.85 SLC2A1 (0.44) PARP1ALDH1A1HPGDNPC1RAB9A
SCHEMBL11541974 0.84 ATM (0.44) PARP1KDM4EALDH1A1HPGDNPC1
SCHEMBL2317568 0.79 CMA1 (0.56) PARP1CSNK2A1CSNK2A2CSNK2BKDM4E
SCHEMBL11537592 0.78 HCRTR1 (0.56) PARP1KDM4EALDH1A1HPGDNPC1
SCHEMBL30445625 0.78 CYP1A2 (0.53) KDM4EALDH1A1THRBHPGDSTS
SCHEMBL68523 0.78 CYP1A2 (0.53) KDM4EALDH1A1THRBHPGDSTS
SCHEMBL118321 0.77 KDM4E (0.53) PARP1CSNK2A1CSNK2A2CSNK2BKDM4E
SCHEMBL11540800 0.77 MEN1 (0.47) KDM4EALDH1A1HPGDNPC1SMN1; SMN2
SCHEMBL28453627 0.77 STS (0.49) KDM4EALDH1A1THRBHPGDSTS
SCHEMBL6238535 0.74 KDM4E (0.40) PARP1KDM4EALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4140532-A ORGANIC SILVER SALT, CATALYST, REDUCING AGENT, 2H-1,3-BENZOTHIAZIN-2,4(3H-)DIONE FUJI PHOTO FILM CO., LTD. (JP) 1979-02-20 US claimed
US-4140532-A ORGANIC SILVER SALT, CATALYST, REDUCING AGENT, 2H-1,3-BENZOTHIAZIN-2,4(3H-)DIONE FUJI PHOTO FILM CO., LTD. (JP) 1979-02-20 US disclosed