⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22538 | 0.93 | — | — | |
| SCHEMBL6775241 | 0.93 | — | — | |
| Ammonia Solution, Strong SCHEMBL423247 | 0.86 | — | — | |
| SCHEMBL28232663 | 0.86 | — | — | |
| Bromide SCHEMBL3220866 | 0.86 | — | — | |
| SCHEMBL1846005 | 0.86 | — | — | |
| Phosphine SCHEMBL21056494 | 0.86 | — | — | |
| SCHEMBL830743 | 0.77 | — | — | |
| SCHEMBL6230396 | 0.77 | — | — | |
| SCHEMBL1013573 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 342 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119823156-A | Synthesis method of 2- (4- (tert-butyl) naphthalene-2-yl) -4, 5-tetramethyl-1, 3, 2-dioxaborane | 奥盖尼克材料(苏州)有限公司 | 2025-04-15 | — | — | CN | claimed |
| CN-119039340-A | Preparation method of diethylamino trialkoxysilane | 湖北华邦化学有限公司 | 2024-11-29 | — | — | CN | claimed |
| CN-118459515-A | Preparation method of 2 '-azidoamide-6' -mannoside-phosphate compound | 杭州瑞奥生物医药有限公司 | 2024-08-09 | — | — | CN | claimed |
| CN-113024452-B | OLED display material intermediate 4-tertiaryamyl-2-bromopyridine and synthesis method thereof | 阜阳欣奕华材料科技有限公司 | 2024-06-11 | — | — | CN | claimed |
| CN-113683639-B | Process method for synthesizing tri-tert-butyl phosphorus tetrafluoroborate | 大连双硼医药化工有限公司 | 2024-03-26 | — | — | CN | claimed |
| CN-117623838-A | Chiral sulfoxide ester compound and preparation method thereof | 贵州大学 | 2024-03-01 | — | — | CN | claimed |
| CN-117164586-B | Preparation method of spiro diamine | 苏州凯瑞医药科技有限公司 | 2024-02-06 | — | — | CN | claimed |
| CN-113166037-B | Method for producing amine by amide reduction | 高砂香料工业株式会社 | 2023-12-29 | — | — | CN | claimed |
| CN-117164586-A | Preparation method of spiro diamine | 苏州凯瑞医药科技有限公司 | 2023-12-05 | — | — | CN | claimed |
| CN-114605240-B | Preparation method of esketamine hydrochloride synthesis intermediate | 宜昌人福药业有限责任公司 | 2023-06-06 | — | — | CN | claimed |
| WO-2014061034-A1 | PROCESS FOR PREPARATION OF BOCEPREVIR AND INTERMEDIATES THEREOF | MSN LABORATORIES LIMITED (IN) | 2014-04-24 | — | — | WO | claimed |
| EP-1255747-B1 | SYNTHESIS OF 3,6-DIALKYL-5,6-DIHYDRO-4-HYDROXY-PYRAN-2-ONE | HOFFMANN LA ROCHE (CH) | 2006-10-04 | — | — | EP | claimed |
| US-20030171602-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one | ROCHE COLORADO CORPORATION | 2003-09-11 | — | — | US | claimed |
| US-20030158423-A1 | Synthesis of 3,6-dialkyl-5,6-dihydro-4-hydroxy-pyran-2-one | ROCHE COLORADO CORPORATION (US) | 2003-08-21 | — | — | US | claimed |
| US-20030158422-A1 | Process for enantioselectively producing the (R)-delta-lactone | ROCHE COLORADO CORPORATION | 2003-08-21 | — | — | US | claimed |
| JP-2003521546-A | — | — | 2003-07-15 | — | — | JP | claimed |
| US-6545165-B1 | Cyclization | ROCHE COLORADO CORPORATION | 2003-04-08 | — | — | US | claimed |
| CN-1396919-A | Synthesis method of 3, 6-dialkyl-5, 6-dihydro-4-hydroxy-pyran-2-ketone | HOFFMANN LA ROCHE (CH) | 2003-02-12 | — | — | CN | claimed |
| EP-1255747-A2 | SYNTHESIS OF 3,6-DIALKYL-5,6-DIHYDRO-4-HYDROXY-PYRAN-2-ONE | F. HOFFMANN-LA ROCHE AG (CH) | 2002-11-13 | — | — | EP | claimed |
| WO-2001057014-A2 | SYNTHESIS OF 3,6-DIALKYL-5,6-DIHYDRO-4-HYDROXY-PYRAN-2-ONE | F. HOFFMANN-LA ROCHE AG (CH) | 2001-08-09 | — | — | WO | claimed |