Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.70 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | SLC15A2 | Q16348 | 2/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.56 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11538242 | 1.00 | MAPK1 (0.73) | MAPK1ALDH1A1L3MBTL1PLCG1TDP1 | |
| SCHEMBL11187622 | 1.00 | MAPK1 (0.73) | MAPK1ALDH1A1L3MBTL1PLCG1TDP1 | |
| SCHEMBL11282498 | 1.00 | MAPK1 (0.73) | MAPK1ALDH1A1L3MBTL1PLCG1TDP1 | |
| SCHEMBL11187628 | 1.00 | MAPK1 (0.73) | MAPK1ALDH1A1L3MBTL1PLCG1TDP1 | |
| SCHEMBL6881868 | 0.90 | MAPK1 (0.60) | MAPK1ALDH1A1L3MBTL1PLCG1TDP1 | |
| SCHEMBL9697978 | 0.90 | MAPK1 (0.60) | MAPK1ALDH1A1L3MBTL1PLCG1TDP1 | |
| SCHEMBL9369881 | 0.90 | MAPK1 (0.60) | MAPK1ALDH1A1L3MBTL1PLCG1TDP1 | |
| SCHEMBL9698012 | 0.90 | MAPK1 (0.60) | MAPK1ALDH1A1L3MBTL1PLCG1TDP1 | |
| SCHEMBL9369876 | 0.90 | MAPK1 (0.60) | MAPK1ALDH1A1L3MBTL1PLCG1TDP1 | |
| SCHEMBL11867023 | 0.89 | MAPK1 (0.60) | MAPK1ALDH1A1L3MBTL1PLCG1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4159267-A | Novel silyl ester azetidine-2-sulfenate intermediates and process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1979-06-26 | — | — | US | disclosed |
| US-3944545-A | Process for preparing desacetoxycephalosporins | ELI LILLY AND COMPANY (US) | 1976-03-16 | — | — | US | disclosed |
| US-3932392-A | DICYCLOHEXYLAMINE, DIISOPROPYLAMINE | BRISTOL-MYERS COMPANY (US) | 1976-01-13 | — | — | US | disclosed |