Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | UBE2N | P61088 | 2/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11542405 | 0.87 | CNR2 (0.35) | — | |
| SCHEMBL11542458 | 0.86 | NPC1 (0.39) | MAPK1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL11543610 | 0.84 | CNR2 (0.39) | — | |
| SCHEMBL29571473 | 0.82 | MAPT (0.41) | SMN1; SMN2NPC1RAB9ALMNACASP3 | |
| SCHEMBL11541907 | 0.82 | MAPT (0.41) | SMN1; SMN2NPC1RAB9ALMNACASP3 | |
| SCHEMBL11548788 | 0.79 | MAPK1 (0.39) | MAPK1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL11540638 | 0.79 | MAPK1 (0.39) | MAPK1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL20886560 | 0.77 | MAPK1 (0.37) | MAPK1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL11546610 | 0.76 | NPC1 (0.39) | MAPK1SMN1; SMN2NPC1RAB9ALMNA | |
| SCHEMBL11542410 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4178327-A | FIREPROOFING | THE DOW CHEMICAL COMPANY (US) | 1979-12-11 | — | — | US | disclosed |
| US-4054733-A | MOLDING MATERIALS | THE DOW CHEMICAL COMPANY (US) | 1977-10-18 | — | — | US | disclosed |