Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.61 |
| ▸ | NQO1 | P15559 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.33 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31035604 | 0.86 | PTPN1 (0.45) | PTPN1CSNK2A2CSNK2BCSNK2A1ESR1 | |
| SCHEMBL5358403 | 0.76 | PTPN1 (1.00) | PTPN1NQO1CSNK2A2CSNK2BCSNK2A1 | |
| SCHEMBL31298110 | 0.72 | PTPN1 (0.43) | PTPN1MAPT | |
| SCHEMBL26104769 | 0.72 | PTPN1 (0.43) | PTPN1MAPT | |
| SCHEMBL28792827 | 0.72 | PTPN1 (0.54) | PTPN1CSNK2A2CSNK2BCSNK2A1CSNK2A3 | |
| SCHEMBL17734362 | 0.71 | PTPN1 (0.61) | PTPN1CSNK2A2CSNK2BCSNK2A1ALDH1A1 | |
| SCHEMBL29503837 | 0.70 | MAPT (0.55) | PTPN1ALDH1A1MAPTHPGDMAOB | |
| SCHEMBL28442550 | 0.70 | MAPT (0.55) | PTPN1ALDH1A1MAPTHPGDMAOB | |
| SCHEMBL24912992 | 0.69 | PTPN1 (0.43) | PTPN1CSNK2A2CSNK2BCSNK2A1ESR1 | |
| SCHEMBL8171800 | 0.68 | PTPN1 (0.61) | PTPN1CSNK2A2CSNK2BCSNK2A1CSNK2A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153707-A | Fungicidal isoxazolyl phenols and method of use | THE UPJOHN COMPANY (US) | 1979-05-08 | — | — | US | disclosed |