Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 3/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PHLPP1 | O60346 | 1/20 | 0.39 |
| ▸ | ILK | Q13418 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11539376 | 1.00 | AKT1 (0.39) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL23191967 | 0.71 | AKT1 (0.66) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL15042781 | 0.71 | AKT1 (0.66) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL6027769 | 0.71 | AKT1 (0.66) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL5267755 | 0.70 | AKT1 (0.34) | AKT1PDPK1PHLPP1ILK | |
| SCHEMBL11446961 | 0.68 | — | — | |
| SCHEMBL4467672 | 0.66 | AKT1 (0.36) | AKT1PDPK1PHLPP1ILKALOX5 | |
| SCHEMBL5769073 | 0.65 | AKT1 (0.33) | AKT1PDPK1PHLPP1ILK | |
| SCHEMBL5266783 | 0.64 | AKT1 (0.33) | AKT1PDPK1PHLPP1ILK | |
| SCHEMBL5266292 | 0.64 | AKT1 (0.33) | AKT1PDPK1PHLPP1ILK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4153614-A | Synthesis of (S)-(+)-6-hydroxy-2,5,7,8-tetramethylchroman-2-methanol and intermediates therein | HOFFMANN-LA ROCHE INC. (US) | 1979-05-08 | — | — | US | disclosed |