Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APOL1 | O14791 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23619619 | 0.88 | PLG (0.44) | ACEAPOL1DPP4 | |
| SCHEMBL6791984 | 0.82 | ACE (0.61) | ACE | |
| SCHEMBL31285433 | 0.82 | ACE (0.61) | ACE | |
| SCHEMBL2441754 | 0.82 | ACE (0.61) | ACE | |
| SCHEMBL5743553 | 0.82 | ACE (0.61) | ACE | |
| SCHEMBL6039783 | 0.82 | ACE (0.61) | ACE | |
| SCHEMBL2441750 | 0.82 | ACE (0.61) | ACE | |
| SCHEMBL2441752 | 0.82 | ACE (0.61) | ACE | |
| SCHEMBL5743561 | 0.82 | ACE (0.61) | ACE | |
| SCHEMBL8591233 | 0.81 | HTT (0.45) | ACEDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4172143-A | PSYCHOSOMATIC AND PSYCHOLOGICAL DISTURBANCES | SYNTHELABO (FR) | 1979-10-23 | — | — | US | disclosed |